Research Briefs

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The University of Minnesota Transdisciplinary Tobacco Use Research Center (UMN TTURC) is one of eight TTURC affiliates funded through the National Cancer Institute and the National Institute on Drug Abuse. The overall goal of the TTURC is to stimulate integrated research across scientific disciplines, such as the neurosciences, economics, epidemiology, genetics, behavioral sciences, pharmacology, and medicine in order to significantly advance our understanding of tobacco use, nicotine addiction, and tobacco harm reduction.

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Now showing 1 - 7 of 7
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    Environmental tobacco smoke and carcinogen exposure
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2005-05-10) University of Minnesota
    To assess the degree of carcinogen exposure among those individuals working or socializing in smoking environments, scientists at the University of Minnesota conducted two studies, which measured the level of carcinogen uptake in nonsmoking casino patrons and in nonsmoking bar and restaurant employees both before and after exposure to environmental tobacco smoke (ETS). Both studies demonstrated that nonsmokers' exposure to ETS causes significant increases in uptake of tobaccospecific carcinogens and toxins.
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    Reducing cigarette smoking: Research summary Does it reduce cancer risk?
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2004-05-12) University of Minnesota
    To assess whether cutting back on cigarettes reduces the amount of tobacco-specific carcinogens in the body, scientists at the University of Minnesota measured the level of carcinogen uptake in smokers who were reducing their cigarette consumption over 26 weeks. Overall reductions in carcinogen levels were seen, but the levels were modest and were proportionally less than the amount of cigarettes reduced per day.
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    Environmental tobacco exposure in infants
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2006-05-19) University of Minnesota
    To assess the degree of carcinogen uptake in infants aged 3 to 12 months, researchers at the University of Minnesota Transdisciplinary Tobacco Use Research Center (UMN TTURC) measured levels of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (total NNAL) in the urine of infants exposed to ETS in their homes.
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    Cancer-causing agents in new tobacco products
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2006-05-10) Stepanov, I.; Jensen, J.; Hatsukami, Dorothy K.; Hecht, S.S.
    To assess whether new, so-called "reduced exposure" tobacco products contain reduced levels of tobacco-specific cancer-causing agents, scientists at the University of Minnesota measured the level of tobacco-specific nitrosamines (TSNAs) in 19 different brands of tobacco products, including several new varieties.
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    "Light" cigarettes and exposure to carcinogens
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2005-03-09) University of Minnesota
    To assess whether smoking "light" cigarettes reduces the amount of tobacco-specific carcinogens in the body, scientists at the University of Minnesota measured the level of carcinogen uptake in smokers who were using regular, light, and ultralight cigarettes. No significant differences were observed among smokers of the three different types of cigarettes.
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    Modified tobacco products: are they safer?
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2004-06-03) Hatsukami, Dorothy K.
    To assess whether switching to modified tobacco products reduces the amount of tobacco-specific carcinogens in the body, scientists at the University of Minnesota measured carcinogen uptake in smokers who were using either a “reduced exposure” tobacco product (Swedish snuff or the Omni cigarette)or medicinal nicotine. Those using medicinal nicotine had greater reductions. Reductions of carcinogen uptake from modified cigarettes was modest at best.
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    Cigarette reduction: Can it reduce exposure to toxins?
    (University of Minnesota Transdisciplinary Tobacco Use Research Center, 2006-12-22) Hatsukami, Dorothy K.; Le, C.T.; Shang, Y.; Joseph, A.M.; Mooney, M.E.; Carmella, S.G.; Hecht, S.S.
    To assess the degree of compensatory smoking in those who reduce their cigarette intake, researchers at the University of Minnesota Transdisciplinary Tobacco Use Research Center (UMN TTURC)measured levels of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (total NNAL) in the urine of light smokers and of heavy smokers who reduced their cigarette use by at least 40%.