Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period

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Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period

Published Date

2024-02-16

Author Contact

Yoshida, Kyoko
kyoshida@umn.edu

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Dataset
Simulation

Abstract

Heart growth in the pregnant patient helps maintain cardiovascular function while supporting the growing fetus. However, in some cases, the cardiovascular demand of pregnancy can trigger life-threatening conditions, including hypertensive disorders of pregnancy and peripartum cardiomyopathy. We previously developed a computational model that accounts for hormonal and hemodynamic interactions throughout pregnancy to uncover the mechanisms behind this heart growth. Here, we evaluated its breadth, applying it to normal and abnormal rat pregnancies and after delivery. This dataset includes supplemental data and tables that support our findings and accompany our manuscript

Description

Experimental data used in simulations in 'MultiscaleModel.zip' are provided in .csv form in 'LitDataPregnancy.zip', 'LitDataHTN.zip', and 'LitDataPostpartum.zip'.

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Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period (to be submitted)

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National Institute of Health T32-HL139431
American Heart Association 23CDA1048434

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Suggested citation

Kaissar, Molly; Yoshida, Kyoko. (2024). Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period. Retrieved from the Data Repository for the University of Minnesota (DRUM), https://doi.org/10.13020/gqsa-tn55.
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File View/OpenDescriptionSize
Readme_Yoshida_Kaissar.txtDescription of the overall files and data25.92 KB
MultiscaleModel.zipThe MATLAB code files for a multiscale cardiac growth model409.22 MB
LitDataPregnancy.zipCompilation of .csv files defining the experimental data used to simulate normal pregnancy and the data compared against model predictions108.29 KB
LitDataHTN.zipCompilation of .csv files defining the experimental data used to simulate three disease models of hypertensive pregnancy and the data compared against model predictions104.93 KB
LitDataPostpartum.zipCompilation of .csv files defining the experimental data used to simulate the postpartum period and the data compared against model predictions71.69 KB
SupplementalMaterial.zipThe supplemental figures, tables, and references described in Kaissar publication1.5 MB

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