Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period
2024-02-16
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Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period
Published Date
2024-02-16
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Yoshida, Kyoko
kyoshida@umn.edu
kyoshida@umn.edu
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Simulation
Simulation
Abstract
Heart growth in the pregnant patient helps maintain cardiovascular function while supporting the growing fetus. However, in some cases, the cardiovascular demand of pregnancy can trigger life-threatening conditions, including hypertensive disorders of pregnancy and peripartum cardiomyopathy. We previously developed a computational model that accounts for hormonal and hemodynamic interactions throughout pregnancy to uncover the mechanisms behind this heart growth. Here, we evaluated its breadth, applying it to normal and abnormal rat pregnancies and after delivery. This dataset includes supplemental data and tables that support our findings and accompany our manuscript
Description
Experimental data used in simulations in 'MultiscaleModel.zip' are provided in .csv form in 'LitDataPregnancy.zip', 'LitDataHTN.zip', and 'LitDataPostpartum.zip'.
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Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period (to be submitted)
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National Institute of Health T32-HL139431
American Heart Association 23CDA1048434
American Heart Association 23CDA1048434
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Kaissar, Molly; Yoshida, Kyoko. (2024). Model, tables, figures, and data supporting Computational model captures cardiac growth in hypertensive pregnancies and in the postpartum period. Retrieved from the Data Repository for the University of Minnesota (DRUM), https://doi.org/10.13020/gqsa-tn55.
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| File View/Open | Description | Size |
|---|---|---|
| Readme_Yoshida_Kaissar.txt | Description of the overall files and data | 25.92 KB |
| MultiscaleModel.zip | The MATLAB code files for a multiscale cardiac growth model | 409.22 MB |
| LitDataPregnancy.zip | Compilation of .csv files defining the experimental data used to simulate normal pregnancy and the data compared against model predictions | 108.29 KB |
| LitDataHTN.zip | Compilation of .csv files defining the experimental data used to simulate three disease models of hypertensive pregnancy and the data compared against model predictions | 104.93 KB |
| LitDataPostpartum.zip | Compilation of .csv files defining the experimental data used to simulate the postpartum period and the data compared against model predictions | 71.69 KB |
| SupplementalMaterial.zip | The supplemental figures, tables, and references described in Kaissar publication | 1.5 MB |
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