Dr. Martin Dworkin
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Professor
Department of Microbiology
Ph.D., University of Texas-Austin, 1955
dworkin@umn.edu
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Item SERGEI WINOGRADSKY: A FOUNDER OF MODERN MICROBIOLOGY AND THE FIRST MICROBIAL ECOLOGIST(FEMS Microbiology Reviews, 2011-08-11) Dworkin, MartinSergei Winogradsky, was born in Russia in 1856 and was to become a founder of modern microbiology. After his Master’s degree work on the nutrition and growth physiology of the yeast Mycoderma vini at the University of St.Petersburg, he joined the laboratory of Anton DeBary in Strassburg. There he carried out his studies on the sulfur-oxidizing bacterium Beggiatoa which resulted in his formulation of the theory of chemolithotrophy. He then joined the Swiss Polytechnic Institute in Zurich where he did his monumental work on bacterial nitrification. He isolated the first pure cultures of the nitrifying bacteria and confirmed that they carried out the separate steps of the conversion of ammonia to nitrite and of nitrite to nitrate. This led directly to the concept of the cycles of sulfur and nitrogen in Nature. He returned to Russia and there was the first to isolate a free-living dinitrogen-fixing bacterium. In the flush of success, he retired from science and spent 15 years on his familial estate in the Ukraine. The Russian revolution forced him to flee Russia.He joined the Pasteur Institute in Paris where he spent his remaining 24 years initiating and developing the field of microbial ecology. He died in 1952.Item Robert Koch – From Obscurity to Glory to Fiasco(Journal of Opinions, Ideas & Essays (JOIE), 2011-10) Dworkin, MartinRobert Koch went from an obscure country physician to be the discoverer of the etiology of anthrax, the inventor of the technique of pure culture bacteriology and with that to the isolation of the tubercle bacillus and its identification as the etiological agent of tuberculosis. These successes propelled him to world-wide glory. In his search for a cure for tuberculosis, he proposed that tuberculin was such a cure. Unfortunately this turned out to be false, and his continued advocacy was a fiasco. Nevertheless his formulation of the germ theory of disease transformed medicine and led to a remarkable series of successes that clarified the etiology of a large number of infectious diseases.