Autism Spectrum Disorders (Pervasive Developmental Disorders) and vitamin D
2010-11-02
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Autism Spectrum Disorders (Pervasive Developmental Disorders) and vitamin D
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2010-11-02
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Abstract
The Autism Spectrum Disorders (ASD’s) are a group of
neurodevelopmental disorders that result in abnormalities of
socialization, communication and behavior. There has been an
apparent increase in the prevalence of ASD’s in the last 20
years. While the exact etiologies of the ASD’s are not known,
scientists believe that gene/environment interactions are
involved in the development of ASD’s. Genes make some individuals
more susceptible to environmental factors. One environmental
factor that could be involved in the development of ASD’s is
vitamin D deficiency during pregnancy and early childhood
development. Vitamin D is an important neurosteroid involved in
brain development. Animal studies have shown that gestational
vitamin D deficiency results in offspring with anatomical
abnormalities similar to those found in autism. Developmental
vitamin D deficiency has been found to dysregulate 36 proteins
involved in mammalian brain development. Vitamin D
supplementation during pregnancy and throughout childhood could
possibly help prevent some cases of ASD.
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The information provided in this handout does not necessarily reflect the views of the University of Minnesota Medical School physicians and faculty. These materials are provided for informational purposes only and are in no way intended to take the place of the advice and recommendations of your personal health care provider. You use the information provided in these handouts at your own risk.
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Miller, Barrie. (2010). Autism Spectrum Disorders (Pervasive Developmental Disorders) and vitamin D. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/95935.
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