Browsing by Author "Ponder, Julia"

Now showing 1 - 4 of 4
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    Data supporting: Evaluation of neurobehavioral abnormalities and immunotoxicity in response to oral imidacloprid exposure in domestic chickens (Gallus callus domesticus)
    (2021-05-10) Franzen-Klein, Dana M; Jankowski, Mark; Roy, Charlotte L; Nguyen-Phuc, Hoa; Chen, Da; Neuman-Lee, Lorin; Redig, Patrick; Ponder, Julia; franz337@umn.edu; Franzen-Klein, Dana M; The Raptor Center
    Domestic chickens (Gallus gallus domesticus) were exposed to imidacloprid by gavage once daily for 7 consecutive days at 0, 0.03, 0.34, 3.42, 10.25, and 15.50 mg/kg/day (n = 20 per group; 5 6-week-old males, 5 6-week-old females, 5 9-week-old males, and 5 9-week-old females). The severity and duration of neurobehavioral abnormalities were recorded. Components of the innate and adaptive immune system were assessed with 7 standard functional assays. Temporary neurobehavioral abnormalities were observed in a dose-dependent manner, including muscle tremors, ataxia, and depressed mentation. The effective dose value for the presence of any neurobehavioral abnormalities in 50% of the test group (ED50) was 4.62 ± 0.98 mg/kg/day. The ED50 for an adjusted score that included both the severity and duration of neurobehavioral abnormalities was 11.24 ± 9.33 mg/kg/day. These ED50 values are equivalent to a 1 kg bird ingesting 29 or 70 imidacloprid treated soybean seeds respectively. Immunotoxicity was not documented, either because the assays were insensitive, did not test relevant immune functions, or imidacloprid is not immunotoxic at this dosing schedule in this species. Neurobehavioral abnormalities were a more sensitive indicator of the sublethal effects of imidacloprid than immunotoxicity.
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    Hunting Ammunition and Implications for Public Health
    (Food Policy Research Center, 2014-02) Ponder, Julia
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    Monitoring the spatiotemporal patterns of wildlife health using rehabilitation databases
    (2022-04-07) Kanankege, Kaushi; Willette, Michelle; Jenni, Phil; Ponder, Julia; Schott, Renee; Bueno, Irene; Muellner, Ulrich; Muellner, Petra; VanderWaal, Kimberly; kanan009@umn.edu; Kanankege, Kaushi; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota
    Wildlife health surveillance is challenging. An alternative is to use wildlife rehabilitation data as potential sentinels, where anomalies in the pattern of submissions may indicate an underlying event that deviates from the baseline and warrants further investigation. Such anomalies may affect multiple species, leading submissions to be clustered in a certain area or time period. To determine spatiotemporal submission patterns and the feasibility of identifying anomalies potentially associated with underlying events, we aggregated databases from two major wildlife rehabilitation centers in Minnesota, drawing on 66,472 submissions from the 2015 – 2019 period, and pertaining to 29 ”species groups” and 12 “circumstances” associated with submission. The infants and juveniles of wildlife, including fledglings, hatchlings, and after-hatch year birds (raptor-specific), submitted as a group from the same location on the same day were grouped and considered as one submission. Hence, the number of records included in the spatiotemporal cluster analysis was 49,352. The multivariate multinomial space-time model of the scan statistic was used to identify statistically significant spatiotemporal clusters of either wildlife species groups or circumstances, simultaneously (Cluster: an area capturing 10% of the submissions aggregated within a maximum radius of 30km during a maximum temporal window of 3-months). This repository contains the data arranged to be used for the spatial cluster analysis.