Between Dec 19, 2024 and Jan 2, 2025, datasets can be submitted to DRUM but will not be processed until after the break. Staff will not be available to answer email during this period, and will not be able to provide DOIs until after Jan 2. If you are in need of a DOI during this period, consider Dryad or OpenICPSR. Submission responses to the UDC may also be delayed during this time.

Browsing by Author "Demova, Jiva"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Fear-Potentiated Startle Paradigm in Mice
    (2012-02-27) Zimbel, Max; Demova, Jiva
    TUF1 is a novel neuropeptide highly concentrated in the amygdala, hippocampus, hypothalamus, and the endocrine tissue. Due to the high concentration in these regions, it is believed that TUF1 may play a role in stress regulation and fear-learning. Fear-learning is a form of Classical Conditioning. Fear is measured by Fear-Potentiated Startle (FPS). FPS is a valid and reliable method of measuring fear in rats. This study was conducted in the attempt to create a working FPS paradigm for mice in the Gewirtz Lab. After establishing this paradigm, we should be able to study the effects of TUF1 more efficiently using TUf1 knock-out mice.