Anatomical, Biomechanical, and End-of-Life Considerations for Emergent Cardiac Pacing Technologies

Mattson, Alexander
2018-07

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Supplemental Clip 9--Retrieval of a Chronically Implanted Leadless Pacemaker.mp4 (203.4 MB)
Supplemental_Clip_5_His_Bundle_Pacing_in_a_Reanimated_Human_Heart.mp4 (243.83 MB)
Supplemental_Clip_10_Atraumatic_Tine_Extraction_from_the_Tricuspid_Valve.wmv (1.54 MB)

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Anatomical, Biomechanical, and End-of-Life Considerations for Emergent Cardiac Pacing Technologies

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2018-07

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Over 600,000 permanent pacing systems are implanted each calendar year as the primary therapy for symptomatic bradycardia. Innovations in pacing technology have rapidly expanded the indications for this life-saving therapy, while reducing complication rates. This thesis examined three prongs of emergent pacing technologies: leadless pacing, epicardial/extravascular pacing, and physiologic pacing through the bundle of His. First, I quantitatively evaluated the likely target anatomies for next-generation pacing systems. Then, anatomic data was supplemented with biomechanics, to provide the foundation upon which next-generation leadless pacemaker fixation mechanisms may be built. Finally, I investigated some of the challenges of extracting leadless pacing systems. The data in this thesis provided a substrate for the design and implementation of next-generation pacing systems.

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University of Minnesota Ph.D. dissertation. July 2018. Major: Biomedical Engineering. Advisor: Paul Iaizzo. 1 computer file (PDF); xvii, 196 pages + 3 supplementary files.

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Mattson, Alexander. (2018). Anatomical, Biomechanical, and End-of-Life Considerations for Emergent Cardiac Pacing Technologies. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/216362.

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