Development of an Analytical Assay for the Determination of Vinpocetine’s Primary Metabolite, Apovincaminic Acid, in Human Plasma

Gao, Robert
Paz, Matt
2012-04-18
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Development of an Analytical Assay for the Determination of Vinpocetine’s Primary Metabolite, Apovincaminic Acid, in Human Plasma

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2012-04-18

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Vinpocetine (VP) is a derivative obtained from (+) vincamine, and is commonly extracted from periwinkle. It has been shown to alleviate risks associated with stroke by enhancing cerebral blood flow. VP is also useful for the treatment of epilepsy and for the prevention of dementia. Current research is examining whether VP’s therapeutic effect is due to its active metabolite, AVA.

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Faculty Adviser: Dr. Susan Marino

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This research was supported by the Undergraduate Research Opportunities Program (UROP).

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Gao, Robert; Paz, Matt. (2012). Development of an Analytical Assay for the Determination of Vinpocetine’s Primary Metabolite, Apovincaminic Acid, in Human Plasma. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/133454.

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