Testing the Hydrolysis-Driven Degradation of Sutures: Impacts on Tensile Strength Over Time

Abstract

This study investigates the rate of tensile strength loss in absorbable sutures due to hydrolytic degradation under simulated in vivo conditions. Sutures were subjected to tensile and degradation testing in a controlled environment to evaluate the impact of moisture and time on suture performance. Results indicate an initial increase in tensile strength upon hydration, followed by a progressive decline due to hydrolysis. These findings provide critical insights for surgeons regarding suture performance in high-stress environments, such as the fascia layer, and underscore the need for further research in dynamic loading and in vivo scenarios.