Preparation of Gold-coated Magnetic Nanorods for Lung Cancer Treatment

Loading...
Thumbnail Image

Persistent link to this item

Statistics
View Statistics

Journal Title

Journal ISSN

Volume Title

Title

Preparation of Gold-coated Magnetic Nanorods for Lung Cancer Treatment

Published Date

2012-04-18

Publisher

Type

Presentation

Abstract

Gold-coated magnetic nanorods are a possible means for achieving selective destruction of lung cancer cells through plasmon resonance. These particles can be delivered to the lung by inhalation and can be detected by the non-invasive imaging technique of magnetic resonance imaging (MRI). In this study, experimental methods were evaluated for the preparation gold coated nanorods. Iron chloride salts, FeCl2 or FeSO4, were dissolved and then precipitated with base. Ammonium or potassium nitrate was added to oxidize the precipitated ferrous oxides along with various polyethylene glycols to yield selective magnetite particles (Fe3O4) with needle-like morphology. The magnetic nanorods were recovered and coated with gold by adding the mild reducing agent, hydroxylamine, in the presence of tetrachloroaurate (HAuCl4). The thickness of the gold layer can be controlled by the particle concentration and amount of gold added. The particles are then characterized in terms of composition, size, shape, induced magnetization and light absorption.

Description

Faculty mentor: Timothy Wiedmann

Related to

Replaces

License

Series/Report Number

Funding information

This research was supported by the Undergraduate Research Opportunities Program (UROP).

Isbn identifier

Doi identifier

Previously Published Citation

Suggested citation

Fakhoury, Joanna. (2012). Preparation of Gold-coated Magnetic Nanorods for Lung Cancer Treatment. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/132227.

Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.