Polarization-sensitive optical coherence tomography using polarization-maintaining fibers

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https://hdl.handle.net/11299/99238

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Polarization-sensitive optical coherence tomography using polarization-maintaining fibers

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Al-Qaisi, Muhammad K.

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2010-12

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Abstract

Optical Coherence Tomography (OCT) is a sensitive imaging technique that generates cross-sectional images of turbid tissues with a micrometer-scale resolution. Polarization-Sensitive (PS) OCT adds additional contrast to OCT by detecting polarization alterations within tissues, and provides accurate OCT images in polarization-altering tissues. Common approaches to build PSOCT are either: simple but difficult to incorporate in clinics and laboratories, or fiber-based and flexible but expensive, sophisticated, and computationally demanding. We have developed a new approach to build PSOCT using Polarization-Maintaining Fibers (PMF). A single depth scan is sufficient to calculate reflectivity, retardance, and axis orientation information using computationally-inexpensive algorithms. We present novel PMF-based PSOCT systems and demonstrate sensitivity figures larger than 100 dB, equivalent to common approaches. The developed PMF-based interferometers are used to measure minute Faraday rotations in tissue-mimicking phantoms, and the polarization properties of unmyelinated nerves. A novel algorithm is also developed to correct for errors calculating the birefringence of samples, and generate interpretable PSOCT images.

Keywords

Birefringence

Faraday effect

Imaging

Phase measurement

Polarization

Polarization-sensetive optical coherence tomography

Biomedical Engineering

Description

University of Minnesota Ph.D. dissertation. December 2010. Major: Biomedical Engineering. Advisor: Taner Akkin. 1 computer file (PDF); xxii, 171 pages, appendices A-D. Ill. (some col.)

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Al-Qaisi, Muhammad K.. (2010). Polarization-sensitive optical coherence tomography using polarization-maintaining fibers. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/99238.

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