Comparative genomics of Ornithobacterium rhinotracheale and determination of strain-specific pathogenicity and virulence

Loading...

View/Download File

Smith_umn_0130E_22846.pdf (1.87 MB)

Persistent link to this item

https://hdl.handle.net/11299/225878

Statistics

View Statistics

Journal Title

Journal ISSN

Volume Title

Title

Comparative genomics of Ornithobacterium rhinotracheale and determination of strain-specific pathogenicity and virulence

Authors

Smith, Emily

Published Date

2021-09

Publisher

Type

Thesis or Dissertation

Abstract

The subsequent chapters of this dissertation will address many of the current knowledge gaps surrounding ORT. First, comparative genomics of clinical ORT isolates from several US commercial turkey producers will highlight the genetic similarities and differences between currently circulating ORT strains. Second, a study comparing these clinical isolates to commensal isolates of ORT will reveal whether there are genetic differences between clinical and commensal isolates. Finally, a series of challenge studies will determine if clinical ORT strains that differ genomically result in differences clinically, and if controlled exposure is effective in preventing negative outcomes associated with ORT.

Keywords

Bioinformatics

Infectious disease

Microbial genomics

Molecular biology

Poultry

Veterinary science

Description

University of Minnesota Ph.D. dissertation. September 2021. Major: Veterinary Medicine. Advisor: Timothy Johnson. 1 computer file (PDF); viii, 169 pages.

Related to

Replaces

License

Collections

Dissertations

Series/Report Number

Funding information

Isbn identifier

Doi identifier

Previously Published Citation

Suggested citation

Smith, Emily. (2021). Comparative genomics of Ornithobacterium rhinotracheale and determination of strain-specific pathogenicity and virulence. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/225878.

Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.