Cortical representations of social deficits gated by cerebellum dysregulation (2021-03-05)
Loading...
View/Download File
Persistent link to this item
Statistics
View StatisticsJournal Title
Journal ISSN
Volume Title
Title
Cortical representations of social deficits gated by cerebellum dysregulation (2021-03-05)
Published Date
2021
Publisher
Type
Other
Abstract
Patients who suffer neuropsychiatric disorders, including autism, schizophrenia, depression and Alzheimer's disease, often show abnormal social interaction. Therefore, it is important to understand the neural basis of social behavior in search of innovative treatments. Emerging evidence suggests that the cerebellum plays a key role in the neural networks essential for social functions. To investigate the mechanisms, we manipulated the cerebellar activity in a mouse model by precisely controlling the firing of a distinct population of neurons. This manipulation specifically impaired remembrance of previously encountered conspecifics, i.e., social recognition memory. We furthered [sic] delineated the anatomical and functional connections between the cerebellum and the cerebrum that mediate social memory. These insights will help develop clinical interventions for mental illness.
Description
Department of Biology Seminar this Friday, March 5, 2021 at 3:00 pm on Zoom; Speaker: Amy Yang, Assistant Professor at University of Minnesota Duluth Medical School; Hosted by: Dr. Huai Deng; Friday March 5, 2021; This seminar is on Zoom; We encourage you to join us at https://z.umn.edu/scsefriday at 3:00 PM
Related to
Replaces
License
Collections
Series/Report Number
Funding information
Department of Biology
Isbn identifier
Doi identifier
Previously Published Citation
Suggested citation
Yang, Amy; University of Minnesota Duluth. Department of Biology. (2021). Cortical representations of social deficits gated by cerebellum dysregulation (2021-03-05). Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/220625.
Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.