Between Dec 19, 2024 and Jan 2, 2025, datasets can be submitted to DRUM but will not be processed until after the break. Staff will not be available to answer email during this period, and will not be able to provide DOIs until after Jan 2. If you are in need of a DOI during this period, consider Dryad or OpenICPSR. Submission responses to the UDC may also be delayed during this time.
 

Proteolysis of the barley receptor-like protein kinase RPG1 by a proteasome pathway is correlated with Rpg1-mediated stem rust resistance

Loading...
Thumbnail Image

View/Download File

Persistent link to this item

Statistics
View Statistics

Journal Title

Journal ISSN

Volume Title

Title

Proteolysis of the barley receptor-like protein kinase RPG1 by a proteasome pathway is correlated with Rpg1-mediated stem rust resistance

Published Date

2007-06-12

Publisher

Proceedings of the National Academy of Sciences of the United States of America

Type

Article

Abstract

In plants, disease resistance mediated by the gene-for-gene mechanism involves the recognition of specific effector molecules produced by the pathogen either directly or indirectly by the resistance-gene products. This recognition triggers a series of signals, thereby serving as a molecular switch in regulating defense mechanisms by the plants. To understand the mechanism of action of the barley stem rust resistance gene Rpg1, we investigated the fate of the RPG1 protein in response to infection with the stem rust fungus, Puccinia graminis f. sp. tritici. The investigations revealed that RPG1 disappears to undetectable limits only in the infected tissues in response to avirulent, but not virulent pathotypes. The RPG1 protein disappearance is rapid and appears to be due to specific protein degradation via the proteasome-mediated pathway as indicated by inhibition with the proteasomal inhibitor MG132, but not by other protease inhibitors.

Description

Related to

Replaces

License

Series/Report Number

Funding information

Isbn identifier

Doi identifier

10.1073/pnas.0703758104

Previously Published Citation

Nirmala, Jayaveeramuthu, Dahl, Stephanie, Steffenson, Brian J., Kannangara, C. Gamini, Von Wettstein, Diter, Chen, Xianming, & Kleinhofs, Andris. (2007). Proteolysis of the barley receptor-like protein kinase RPG1 by a proteasome pathway is correlated with Rpg1-mediated stem rust resistance.(PLANT BIOLOGY)(Author abstract). Proceedings of the National Academy of Sciences of the United States, 104(24), 10276-10281.

Other identifiers

Suggested citation

Steffenson, Brian; Nirmala, Jayaveeramuthu; Dahl, Stephanie; Kannangara, C.Gamini; Wettstein, Diter von; Chen, Xianming; Kleinhofs, Andris. (2007). Proteolysis of the barley receptor-like protein kinase RPG1 by a proteasome pathway is correlated with Rpg1-mediated stem rust resistance. Retrieved from the University Digital Conservancy, 10.1073/pnas.0703758104.

Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.