Investigating the Effects of NOM1 Deficiency on Human Cell Growth

Loading...

View/Download File

N_Fares_URS2009_Poster.pdf (651.24 KB)

Persistent link to this item

https://hdl.handle.net/11299/50380

Statistics

View Statistics

Journal Title

Journal ISSN

Volume Title

Title

Investigating the Effects of NOM1 Deficiency on Human Cell Growth

Authors

Fares, Nancy

Published Date

2009-04-08

Publisher

Type

Presentation

Abstract

NOM1 (Nucleolarprotein with MIF4G domain 1) is a MIF4G/MA3 protein identified at the chromosome 7q36 breakpoint involved in 7;12 translocations associated with certain acute childhood leukemias. Hypothesis: Since NOM1 homologs are essential in both Saccharomyces cerevisiae and Caenorhabditis elegans, and since NOM1 interacts with a number of proteins involved in ribosome biogenesis, we predict that NOM1 is essential in human cells and that NOM1 deficiency will lead to decreased cell growth.

Keywords

College of Biological Sciences

Microbiology

Department of Genetics, Cell Biology and Development

Description

Additional contributors: Mark Peterson; Kathleen Conklin (faculty mentor).

Related to

Replaces

License

Collections

UMTC Undergraduate Research Presentations and Papers (UROP)

Series/Report Number

Funding information

Isbn identifier

Doi identifier

Previously Published Citation

Suggested citation

Fares, Nancy. (2009). Investigating the Effects of NOM1 Deficiency on Human Cell Growth. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/50380.

Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.