Investigating the Effects of NOM1 Deficiency on Human Cell Growth
2009-04-08
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Investigating the Effects of NOM1 Deficiency on Human Cell Growth
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2009-04-08
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NOM1 (Nucleolarprotein with MIF4G domain 1) is a MIF4G/MA3 protein identified at the chromosome 7q36 breakpoint involved in 7;12 translocations associated with certain acute childhood leukemias. Hypothesis: Since NOM1 homologs are essential in both Saccharomyces cerevisiae and Caenorhabditis elegans, and since NOM1 interacts with a number of proteins involved in ribosome biogenesis, we predict that NOM1 is essential in human cells and that NOM1 deficiency will lead to decreased cell growth.
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Additional contributors: Mark Peterson; Kathleen Conklin (faculty mentor).
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Fares, Nancy. (2009). Investigating the Effects of NOM1 Deficiency on Human Cell Growth. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/50380.
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