Peak shear and peak flow mediated dilation: a time course relationship
2014-05
Loading...
View/Download File
Persistent link to this item
Statistics
View StatisticsJournal Title
Journal ISSN
Volume Title
Title
Peak shear and peak flow mediated dilation: a time course relationship
Authors
Published Date
2014-05
Publisher
Type
Thesis or Dissertation
Abstract
Flow-mediated dilation (FMD) is a measure of endothelial function. This study aimed to explore the temporal relationship of time to peak FMD (FMDTTP) as well as time to peak shear stress (ShearTTP) between children and adults. Shear stress and FMD was assessed in 122 children and 350 adults using ultrasound. A p-value of 0.05 denoted significance. Peak FMD (p=0.022) and Peak Shear rate (p=0.0002), and were significantly larger in children than adults. FMDTTP was significantly slower (p=0.027) in children vs. adults. ShearTTP was slower in children than in adults (p=0.004). There was no significant difference (p=0.27) in time from ShearTTP to FMDTTP between children and adults. In the present showed children not only displayed a larger peak FMD, but also the time it takes the shear stimulus to reach its peak is significantly slower in children than adults. However, the time from peak Shear to peak FMD was similar.
Description
University of Minnesota M.S. thesis. May 2014. Major: Kinesiology. Advisor: Donald R. Dengel, Ph.D. 1 computer file (PDF); v, 43 pages.
Related to
Replaces
License
Series/Report Number
Funding information
Isbn identifier
Doi identifier
Previously Published Citation
Suggested citation
Evanoff, Nicholas George. (2014). Peak shear and peak flow mediated dilation: a time course relationship. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/165467.
Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.