Cyclic AMP dependent Protein Kinase A (PKA) mutant associated with Fibrolamellar Hepatocellular carcinoma (FLHCC): Structure, dynamics and in cell studies.
2020-03
Loading...
View/Download File
Persistent link to this item
Statistics
View StatisticsJournal Title
Journal ISSN
Volume Title
Title
Cyclic AMP dependent Protein Kinase A (PKA) mutant associated with Fibrolamellar Hepatocellular carcinoma (FLHCC): Structure, dynamics and in cell studies.
Authors
Published Date
2020-03
Publisher
Type
Thesis or Dissertation
Abstract
The overall goal of this thesis is to gain a better understanding of the structure, dynamics and function of PKA-DNAJB1 in vitro and in vivo, using human PKA-WT as reference for the studies. I have utilized NMR for most of structural and dynamics studies, ITC for binding experiments and Phosphoproteomics for in vivo studies.
Description
University of Minnesota Ph.D. dissertation. March 2020. Major: Biochemistry, Molecular Bio, and Biophysics. Advisors: David Thomas, Reuben Harris. 1 computer file (PDF); vi, 148 pages.
Related to
Replaces
License
Collections
Series/Report Number
Funding information
Isbn identifier
Doi identifier
Previously Published Citation
Other identifiers
Suggested citation
Karamafrooz, Adak. (2020). Cyclic AMP dependent Protein Kinase A (PKA) mutant associated with Fibrolamellar Hepatocellular carcinoma (FLHCC): Structure, dynamics and in cell studies.. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/217138.
Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.