Distribution of Renin in Rat Adipose Tissue

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Distribution of Renin in Rat Adipose Tissue

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Obesity and hypertension are two leading international health problems of particular concern within the United States. Obesity is often a precursor to high blood pressure which is regulated in part by the renin angiotensin system (RAS). Recent studies have also implicated the RAS as a regulator of body adiposity in human and rodent models. Adipose (fat) tissue has been shown to display a fully functional RAS with the discovery of mRNA for renin, angiotensinogen, angiotensin converting enzyme (ACE) and angiotensin II receptor expression in adipocytes (fat cells). However, it is not yet known where renin is distributed within fat tissue. The aim of this study is to analyze the distribution of renin in components of fat tissue.


Additional contributor: Stephen A. Katz (faculty mentor)

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This research was supported by the Undergraduate Research Opportunities Program (UROP).

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Newman, Krista M.. (2009). Distribution of Renin in Rat Adipose Tissue. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/51443.

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