Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial

Loading...
Thumbnail Image

Persistent link to this item

Statistics
View Statistics

Journal Title

Journal ISSN

Volume Title

Title

Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial

Published Date

2015-05

Publisher

Type

Thesis or Dissertation

Abstract

bold>ABSTRACT</bold> <bold>Objective:</bold> Test the efficacy of a green tea catechin extract (GTE) to improve lipid profile in postmenopausal women. <bold>Methods:</bold> 886 women were enrolled and randomized to consume either 1200 mg of GTE (800 mg EGCG) or placebo, daily. Fasting serum samples were drawn for lipid panel at baseline, midpoint (month 6), and endpoint (month 12) of study for ananlysis. <bold>Results:</bold> After one year on treatment, total cholesterol (-4.6 mg/dL, P<.0001), LDL-C (-5.0 mg/dL, P<.0001), and non-HDL cholesterol (-4.4 mg/dL, P>.0001) were significantly reduced in the GTE group. The largest reductions in TC, LDL-C, and non-HDLC occurred in participants with baseline total cholesterol >200 mg/dL. HDL-C decreased slightly in the GTE group, both after 6 months on treatment (P=.0016), and overall (P=.0038). <bold>Conclusion:</bold> Daily supplementation of GTE at 1200 mg (800 mg EGCG) for one year significantly reduced levels of TC, LDL-C, and non-HDLC in a population of postmenopausal women.

Description

University of Minnesota Master of Science thesis. May 2015. Major:Nutrition. Advisor: Mindy S. Kurzer, PhD. 1 computer file (PDF); vii, 91 pages, appendices 1-2.

Related to

Replaces

License

Series/Report Number

Funding information

Isbn identifier

Doi identifier

Previously Published Citation

Suggested citation

Rose, April Lynn. (2015). Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/172623.

Content distributed via the University Digital Conservancy may be subject to additional license and use restrictions applied by the depositor. By using these files, users agree to the Terms of Use. Materials in the UDC may contain content that is disturbing and/or harmful. For more information, please see our statement on harmful content in digital repositories.