Comparison of Carbonylation in Young and Old Rat Skeletal Muscle

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Comparison of Carbonylation in Young and Old Rat Skeletal Muscle

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2010-04-21

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Reactive oxygen species (ROS) are a natural byproduct of aerobic cellular metabolism. They are highly reactive molecules which cause oxidative damage, such as carbonylation, to proteins, lipids and DNA. Because of the high metabolism and energy demand of skeletal muscle, it is especially susceptible to the carbonylation. Thus, the level of carbonylation can be used as a quantitative estimate of the amount of oxidative damage to the tissue.

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Additional contributors: Edgar Arriaga (faculty mentor); LaDora Thompson (faculty mentor).

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Brancel, Kiara. (2010). Comparison of Carbonylation in Young and Old Rat Skeletal Muscle. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/61699.

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