Browsing by Subject "canine brain tumor"

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    Transcriptomic data from RNA Sequencing of canine high grade glioma tumor samples
    (2024-11-15) Arnold, Susan A; Pluhar, G. Elizabeth; Abrahante Llorens, Juan E; saarnold@umn.edu; Arnold, Susan; University of Minnesota Canine Brain Tumor Program
    These files contain the raw data for bulk RNA sequencing performed on canine high grade glioma tumor samples. These samples were obtained from three breeds of dogs: French bulldogs, boxers, and Boston terriers. All dogs were enrolled in immunotherapy clinical trials within the University of Minnesota Canine Brain Tumor Program. They were obtained from two different time points relative to treatment: pre-treatment and post-treatment. Treatment consisted of surgical resection and immunotherapy. The purpose of these data are to provide a comprehensive profile of how canine high grade glioma transcriptomes change in response to immunotherapy treatment, and to determine if there are breed-associated changes in differential gene expression.