Browsing by Subject "Metamorphosis"
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Item Activin signaling promotes the competence of the prothoracic gland during Drosophila metamorphosis(2010-08) Gibbens, Ying YeIn insects, the timing of metamorphosis is modulated by a large titer of the steroid hormone ecdysone produced by the prothoracic gland. However, the molecular mechanisms that control production of the ecdysone titer are not completely understood. Here we show that blocking Activin signaling in Drosophila prothoracic gland causes developmental arrest prior to metamorphosis. This defect is due to the absence of the ecdysone titer, a likely consequence of reduced expression of the ecdysone biosynthetic enzymes. We further demonstrate that Activin signaling may regulate the competence of the prothoracic gland to respond to prothoracicotropic hormone and insulin, two hormonal signals that have been shown to trigger ecdysone synthesis. These findings suggest that Activin signaling is required for insect metamorphosis by providing competence that allows tissue- and stage-specific response to metamorphic stimuli.Item Always look on the bright side of death: violence, death, and supernatural transformation in Ovid's Fasti(2015-02) Beek, Anna EverettOvid's Fasti, in its elaboration of mythic stories and the aetia of Roman religious practices, exhibits a marked correlation between violence and supernatural transformation: people who experience acts of intense violence such as rape, assault, and bodily mutilation are transformed by the experience into gods or other supernatural beings. In fact, within the Fasti, nearly all apotheoses have an episode of violence as a catalyst, and moreover nearly all violence results in transformation. Although rape (and some other forms of violence) in the Fasti has been examined extensively by other scholars, previous studies have focused on the perpetration of violence, while this dissertation examines the consequences of the event, how the victims fail to re-integrate to society and are removed by being ostracized, exiled, killed, transformed, or even apotheosed because a return to their former lives is impossible. Some of the prominent examples treated are Romulus, Anna Perenna, Ino, Callisto, and Lara. Special attention is paid to how this overarching pattern differentiates the Fasti from Ovid's best known collection of mythic transformation stories, the Metamorphoses. The Metamorphoses does provide several episodes of apotheosis (such as those of Hercules, Aeneas, Romulus, and Julius Caesar), and those episodes share certain structural elements that recur in similar episodes in the Fasti: in many cases, the character in question is put in life-threatening danger, which is averted at the last minute by divine intervention and transformation into divinity. Nevertheless, the Fasti, unlike the Metamorphoses, has almost no episodes of humans being transformed into plants, birds, stones, or geographic features as salvation from a threat or punishment for transgression. On the contrary, transformation is almost exclusively a vehicle to divinity or catasterism. The Fasti's strong association of violence with apotheosis and vice versa enshrines violence within the Roman calendar and even celebrates it as a path to a greater destiny.