Browsing by Author "Springer, Nathan M."

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    Data for: Meta gene regulatory networks in maize highlight functionally relevant regulatory interactions
    (2020-03-12) Zhou, Peng; Springer, Nathan M.; zhoux379@umn.edu; Zhou, Peng; University of Minnesota Springer Lab
    Regulation of gene expression is central to many biological processes. Gene regulatory networks (GRNs) link transcription factors (TFs) to their target genes and represent a map of potential transcriptional regulation. A consistent analysis of a large number of public maize transcriptome datasets including >6000 RNA-Seq samples was used to generate 45 co- expression based GRNs that represent potential regulatory relationships between TFs and other genes in different populations of samples (cross-tissue, cross-genotype, tissue-and-genotype, etc). While these networks are all enriched for biologically relevant interactions, different networks capture distinct TF-target associations and biological processes.