Browsing by Author "Krasutsky, Pavel A"

Now showing 1 - 3 of 3
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    Chemical Extractives Program: A Proposal to Utilize Chemicals Isolated from Birch Bark as a Therapeutic Treatment against Pathogenic Herpes Virus
    (University of Minnesota Duluth, 1999-07) Krasutsky, Pavel A
    The overall goal of this project to Utilize Chemicals Isolated from Birch Bark as a Therapeutic Treatment against Pathogenic Herpes Virus. More specifically the goal of the proposed investigation will be to synthesize 45-50 betulin/ allobetulin prodrugs of increased hydrophiloic character, confirm the structure properties of each new compound and perform the necessary biological testing to identify the top 2-3 candidates to move forward the clinical trials.
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    Paleolimnology of the St. Louis River Estuary
    (University of Minnesota Duluth, 2016-05) Reavie, Euan D; Alexson, Elizabeth; Axler, Richard P; Yost, Chad; Ladwig, Jammi; Nurse, Andrea; Estepp, Lisa; Krasutsky, Pavel A; Kennedy, Kathleen; Yemets, Sergiy; Engstrom, Daniel R
    The St. Louis River Watershed which drains to the St. Louis River and its associated estuary near Lake Superior has more than 150 years of human development history since Euro‐Americans first settled there, resulting in critical water quality impacts. In 1987, the U.S. Environmental Protection Agency designated the St. Louis River as an Area of Concern primarily due to that history which entailed inappropriate discharge of untreated wastewater and debris from poor industrial and community practices. The organic matter loading from inadequate treatment of sewage and paper mill products along with the dumping of woody debris from sawmills contributed to low oxygen levels in the river. The result included devastating impacts to the entire food web from the bacteria to vegetation to invertebrates to fish. Concurrently, poorly managed stormwater runoff from this post‐logged, barren landscape contributed excessive loading of suspended sediments resulting in increased turbidity and nutrient concentrations (e.g., phosphorus, nitrogen) to the river. Since then, government and private entities have taken action to restore the water quality in the St. Louis River Estuary, and to eventually remove the eight remaining SLRAOC BUIs. This summary focuses on the research documenting water quality changes over time associated with the excessive loading of sediment and nutrients BUI.
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    Utilization of Hemicellulose and Cellulose Byproducts of Northern States
    (University of Minnesota Duluth, 2005-09-14) Krasutsky, Pavel A; Lee, Jonathan J
    This proposal is a discovery research program for utilizing polycarbohydrate waste materials and byproducts of North American industries for producing different kinds of carboxymethylcellulose (sodium carboximethylcellulose) for use as a binding agent. The unique idea includes processing CMC formation from the initial cellulose or hemicellulose raw materials, straight through to the application. This can sufficiently decrease the costs of CMC materials from one side, and optimize the necessary properties of CMC products for a particular application. This research will be based on the following high volume hemicellulose and cellulose materials: 1) paper mill sludge (PMS, byproduct of paper mill plants); 2) waste wood molasses (WWM, byproduct from the industry of hardboards); 3) sawdust and wood flour (SWF).