Schettino, Daniella Nvan de Ligt, Jennifer LGSampedro, FernandoShurson, Gerald CUrriola, Pedro E2021-05-252021-05-252019https://hdl.handle.net/11299/220188There is increasing concern regarding the risk of swine disease transmission via feed ingredients, whether imported or domestically produced. This risk may be reduced in the feed ingredient supply chain by identifying and implementing preventive controls (supply chain, sanitation, transportation, and process) at different steps of the chain. The objective of this study was to develop a practical guide to help feed ingredient suppliers and buyers to safely manufacture, package, transport, and use feed ingredients in swine feeding programs. The Food Safety Modernization Act (FSMA) provides the basis of this study because these regulations require proactive risk-based preventive control processes that are applied in the food supply chain to prevent or reduce the risk of hazards from being present in the final product. Using this conceptual framework, implementation of preventive controls in the feed production chain can control or decrease the potential introduction of foreign animal viruses through feed ingredients into the U.S. A decision tree was developed as a first step in identifying preventive controls and potential high-risk feed ingredient sourcing scenarios. A case-study using Porcine Epidemic Diarrhea virus (PEDV) and the corresponding decision tree was developed as an illustration on how to use this new approach. Although this approach is based on swine viral diseases, it can serve as a template for other pathogenic viruses and species.enfeed ingredientsFood Safety Modernization ActFSMApreventive controlsPorcine Epidemic Diarrhea virusswine diseasesGuidelines for developing a risk-based plan to mitigate virus transmission from imported feed ingredientsReport