Clay, Ryan2010-09-152010-09-152010-09-15https://hdl.handle.net/11299/93875The information provided in this handout does not necessarily reflect the views of the University of Minnesota Medical School physicians and faculty. These materials are provided for informational purposes only and are in no way intended to take the place of the advice and recommendations of your personal health care provider. You use the information provided in these handouts at your own risk.Osteoarthritis of the knee is an increasingly common cause of knee pain and disability. Once rest, icing, exercises and pain medicines have failed, many turn to knee injections. Steroid injections have long been the standard therapy for pain reduction, but the benefits are often limited to one to two months, and it is not recommended to have more than three to four steroid injections in the same knee. Hyaluronic acid injections – a synthetic joint lubricant – have been shown to have milder, but longer-lasting pain relief than steroid injections, and may slow the progression of knee degeneration.en-USknee osteoarthritisdegenerative joint diseaseintra-articular corticosteroid injectionintra-articular hyaluronic acid injectionOther