Batdorf, Bjorn2008-11-242008-11-242008-11-24https://hdl.handle.net/11299/45385The information provided in this handout does not necessarily reflect the views of the University of Minnesota Medical School physicians and faculty. These materials are provided for informational purposes only and are in no way intended to take the place of the advice and recommendations of your personal health care provider. You use the information provided in these handouts at your own risk.Post-Lyme syndrome happens in patients who received standard treatment of 2-4 weeks of antibiotics, but still have chronic symptoms. These symptoms include muscle or joint pain, fatigue, memory or thinking difficulty, irritability, difficulty sleeping, depression, headache, or limb weakness. These symptoms occur without lab evidence for them such as markers of inflammation. Some clinicians suggest treatment with months of antibiotics. However, in three large clinical trials, long term treatment with antibiotics was the same as placebo in the treatment of these symptoms. While there currently is no treatment to cure post-Lyme syndrome, it is important for the patient to work closely with their physician to manage the symptoms.en-USantibioticsLyme diseasepost-Lyme syndromeAntibiotic treatment of post-Lyme syndrome is ineffectiveOther