Novi, Vinni ThekkudanAbbas, Abdennour2023-08-042023-08-042023-08V. T. Novi and A. Abbas. Naked-eye visualization of nucleic acid amplicons using hierarchical nanoassembly. Analytical Methods, 2023, DOI: 10.1039/D3AY01050C.https://hdl.handle.net/11299/255770This study reports the development of a rapid visualization method for DNA amplicons. Oligonucleotide-coated gold nanoparticles hierarchically assemble on DNA networks to form globular nanostructures, which precipitate into a distinct visible red pellet. This aims to overcome challenges associated with nanoparticle aggregation and dye-based colorimetric detection in LAMP assays.enArticle10.1039/D3AY01050C