The Search for Novel Cancer Therapies : Catalytic Inhibition of Topoisomerase II by Substituted 9-aminoacridine Derivatives

Etchison, RyanJacobson, BlakeDixon, Joe-JayKratzke, Robert2011-05-252011-05-252011-04-13https://hdl.handle.net/11299/104837The objective of this research is to test the antiproliferative effects of four novel substituted 9-aminoacridine derivatives on lung cancer and to determine their viability as potential therapeutic agents for use in a clinical setting.en-USUniversity of Minnesota Medical SchoolDepartment of MedicineDivision of Hematology, Oncology, and TransplantCollege of Biological SciencesDepartment of Biochemistry, Molecular Biology, and BiophysicsThe Search for Novel Cancer Therapies : Catalytic Inhibition of Topoisomerase II by Substituted 9-aminoacridine DerivativesPresentation