Stein, Jacob2023-09-192023-09-192023-04https://hdl.handle.net/11299/256984University of Minnesota M.S.M.E. thesis. April 2023. Major: Mechanical Engineering. Advisor: Jeffrey Tithof. 1 computer file (PDF); v, 60 pages + 1 supplementary file.In this thesis, a soft porous media experiment is developed to investigate the effect of applying periodic mean-zero pressure gradients to a soft porous medium. These periodic mean-zero pressure gradients are composed of square waves, with a high magnitude positive pressure drop applied for 1/3 of the period and a negative pressure drop with half the magnitude applied for 2/3 of the period. We investigate the effect of varying the pressure magnitude and period. This setup uses a novel tracking method to quantify the porous media and fluid velocities simultaneously, and operates with high levels of accuracy and repeatability. The periodic mean-zero pressure gradients we investigate are shown to generate substantial net flow, in the direction associated with the smaller pressure magnitude portion of the period. The system is also shown to demonstrate hysteretic behavior, where complex packing features form and persist in the solid phase, influencing the results of the system for subsequent experiments. Results from this experiment have important implications for fluid flow in biological tissues, such as interstitial transport in the brain and body, as it demonstrates that small scale, periodic mean-zero pressure gradients can drive significant amounts of net transport through a deformable porous medium.enFluid MechanicsGlymphaticsParticle Tracking VelocimetryPorous MediaNet Flow Through Soft Porous Media Generated by a Periodic Mean-Zero Pressure GradientThesis or Dissertation