Markant, Julie C.2011-01-202011-01-202010-09https://hdl.handle.net/11299/99029University of Minnesota Ph.D. dissertation. September 2010. Major: Child Psychology. Advisor: Kathleen M. Thomas. 1 computer file (PDF); xii, 203 pages.Young infants learn incredible amounts of information as they interact with their environment, often without any explicit instruction. Though researchers have identified mechanisms that support learning about regularities in the environment, it is unclear how these mechanisms contend with the massive amount of potentially relevant stimuli available in the world. Selective attention may constrain early learning, since information that is selectively attended may be preferentially processed by learning mechanisms. Previous studies have relied on social-cueing paradigms to examine learning of selectively attended items. However, attention can also be manipulated in a non-social manner using the spatial cueing paradigm, in which salient spatial cues initiate exogenous shifts of attention. Individuals are typically faster to respond to items appearing in the cued location; however, this facilitation is dependent on the timing between the cue and target presentations. Following relatively short cue-target delays, attention is biased towards targets in the cued location, whereas longer delays bias attention towards targets in the non-cued location, a process known as inhibition of return (IOR). This dissertation consists of two studies. Study 1 examined whether selective attention biases modulate 7-month-old infants’ learning of predictable information. Study 2 addressed individual differences in 7-month-old infants’ sensitivity to spatial cues. Specifically, Study 2A examined the consistency of cueing behavior across repeated testing, while Studies 2B and 2C explored behavioral and genetic factors that may influence variation in infants’ sensitivity to spatial cues. Results of Study 1 indicated that spatial cueing modulated selective attention, with enhanced learning of the item that was preferentially attended. Study 2A demonstrated stability in IOR behaviors when using qualitative (categorical) but not quantitative measures. Studies 2B and 2C found that variations in infants’ sensitivity to spatial cues were related to both individual differences in their reactivity to novel stimuli and genetic polymorphisms that affect the dopamine and acetylcholine neurotransmitter systems. These results highlight the complexity of interactions between early attention and learning processes, the wide array of factors that may impact infants’ responses during a basic attention task, and the range of neural systems that are likely involved in early selective attention.en-USGenetic polymorphismsIndividual differencesInfancyLearningNoveltySelective attentionChild PsychologyThesis or Dissertation