Cellular Identity Validation of NG2-Expressing Glial Cells in the Olfactory Bulb of a CreERT–tdTomato Mouse Model
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Validation of the cellular identity of fluorescently labeled cells in the olfactory bulb of an NG2-CreERT–tdTomato mouse model. This transgenic mouse line uses a tamoxifen-inducible genetic labeling system to permanently mark NG2 glial cells and their descendants with a red fluorescent reporter, allowing for lineage tracing of this glial population. The study sought to confirm that cells were being correctly being marked by the model through immunohistochemical analysis using canonical markers for NG2 glia and astrocytes.
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Project completed in Fall 2025 as a part of the I-UROP program, thanks to the mentorship provided by Laura López-Mascaraque and Raúl Fernández Arias at the Cajal Institute, Madrid.
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This research was supported by the Undergraduate Research Opportunities Program (UROP).
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Long, Fiona. (2025). Cellular Identity Validation of NG2-Expressing Glial Cells in the Olfactory Bulb of a CreERT–tdTomato Mouse Model. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/277736.
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