The volume of a lake is a crucial component in understanding the different biological, chemical, thermal, and hydrologic processes occurring within it. Minnesota has within its border tens of thousands of lakes, but for only a small fraction of those are there any readily available bathymetric information. We applied a previously developed methodology for predicting lake volumes using lake surface area and land surface elevation change for each of the lakes as well as a statistical method to determine total lake volume through the use of bootstrapping for over 40,000 lakes within Central Minnesota spanning from the Twin Cities to Moorhead across 17 HUC-8 watersheds. 816 lakes had known bathymetric data within the watersheds with a range of volumes approximately from 190,000 to 135,000,000 m3 and a range of surface areas from 64,000 to 21,000,000 m2. The total lake volumes for both methods calculated was 1,180,000 and 1,200,000 hectare meters. When comparing the known to the predicted volumes of the 816 lakes, the model explained 82% of the variation. The sum difference between the total predicted lake volume and known volumes using the statistical method was less than 2%. These models are not only an accurate way to estimate lake volume, but a good steppingstone to help calculate different processes that require a volume.