Title
Synthesis of Disubstituted Oxindoles Using the Method of Asymmetric Cyanoamidation
Abstract
Earlier studies demonstrate the ability of cyanoformamides to cyclize into 3,3-disubstituted oxindoles using chiral ligands, a palladium catalyst and Lewis base additives. Unknown, however, is the effect of chiral ligands and Lewis acids on the enantioselectivity of the same reaction. Studying these compounds should provide insight to their function in medicine or pharmaceuticals.
Suggested Citation
Anand, Aarti; Douglas, Christopher.
(2011).
Synthesis of Disubstituted Oxindoles Using the Method of Asymmetric Cyanoamidation.
Retrieved from the University of Minnesota Digital Conservancy,
https://hdl.handle.net/11299/115476.