COVID-19 Clinical Trials

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The University of Minnesota Medical School is currently performing clinical research trials to find treatments for the COVID-19. One of the studies examines a blood pressure medication, losartan, to see if it can help alleviate the severity of the disease. Research focuses on two patient groups: patients admitted to the hospital and patients with mild disease who self-isolate at home. This is a multi-center (M Health Fairview and Hennepin County Medical Center), double-blinded study of COVID-19 infected patients who will be randomized 1:1 to daily losartan or placebo for 10 days or until treatment failure, which is when a patient needs to be admitted to the hospital.

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    Randomized control trial of losartan for inpatients with COVID-19
    (2020-05-01) Tignanelli, Christopher; Puskarich, Michael; ctignane@umn.edu; Tignanelli, Christopher; University of Minnesota Department of Surgery; University of Minnesota Department of Emergency Medicine
    The University of Minnesota Medical School is currently performing clinical research trials to find treatments for the COVID-19. One of the studies examines a blood pressure medication, losartan, to see if it can help alleviate the severity of the disease. This is a multi-center (M Health Fairview and Hennepin County Medical Center), double-blinded study of COVID-19 infected patients who will be randomized 1:1 to daily losartan or placebo for 10 days or until hospital discharge.
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