Welcome to public health moment from the University of Minnesota. A major new clinical trial seeks to determine whether HIV infected individuals with no symptoms have less risk of developing Aids or other illnesses if they begin taking treatments sooner rather than later. Jim Neaton, a University of Minnesota Professor of Biostatistics, will lead the study. There are different recommendations about treating when to treat HIV because the evidence is not robust. That's why you need a very kind of strong study design with randomization, lots of people with long term follow up to really get the answer about risk versus benefit. Here, Dr. Keith Henry, Director of HIV Clinical Research at the Henne County Medical Center, says that risks include side effects, which in rare instances can be deadly. He says that cost is another factor to consider most widely drug in the US right now, a triple, which is a 3.1 drug. And it costs just under $2,000 a month, full retail price, and a year of antichol therapy and monitoring averages about $25,000 And a patient who's doing well, 40 years of that adds up to $1,000,000 for 40 years of successful treatment that's expensive. Having really good data about what groups of patients most benefit is really crucial.