Full GSCAN meta-analysis minus 23andMe: Full meta-analysis of all GSCAN cohorts summary statistics except 23andMe summary statistics. These set of results have been pruned for sites with minor allele frequency greater than 0.001, have an effective sample size of at least 10% of the maximum sample size, overall imputation quality (Effective_N/N) > 0.3 and present in 20 or more studies. The results are also annotated using TabAnno (https://genome.sph.umich.edu/wiki/TabAnno) with UCSC genome browser annotations. We did not include allele frequency for data privacy reasons and instead used HRC allele frequency and 1000G allele frequency where HRC allele frequency is not available for the variant. More detailed information can be found in the Supplementary Text and Figures for Liu et al. (2019): https://doi.org/10.1038/s41588-018-0307-5 File descriptions: DrinksPerWeek.txt.gz: Summary statistics for associations with phenotype DrnkWk, defined as the average number of drinks a participant reported drinking each week, aggregated across all types of alcohol. N=537,349, final number of variants=11,916,706 CigarettesPerDay.txt.gz: Summary statistics for associations with phenotype CigDay, defined as the average number of cigarettes smoked per day, either as a current smoker or former smoker. N=263,954, final number of variants= 12,003,613 SmokingInitiation.txt.gz: Summary statistics for associations with SmkInit, a binary phenotype. Any participant reporting ever being a regular smoker in their life (current or former) were coded a 2 while any participant who reported never being a regular smoker in their life were coded a 1. N=632,802, final number of variants=11,733,344 SmokingCessation.txt.gz: Summary statistics for associations with SmkCes, a binary phenotype with current smokers coded as a 2 and former smokers coded as a 1. N=312,821, final number of variants=12,197,133 AgeOfInitiation.txt.gz: Summary statistics for associations with phenotype AgeSmk, the age at which an individual started smoking cigarettes regularly. N=262,990, final number of variants=11,983,806 Header Information: CHROM: Chromosome POS: Position RSID: rsID REF: Reference allele ALT: Alternate allele AF: Allele Frequency from HRC or 1000G STAT: Chi-square statistic PValue: p-value Beta: Beta based on the alternate allele SE: Standard error of the beta N: Sum of sample size across contributing cohorts Effective_N: Sum of Sample size * imputation r2 across contributing cohorts Number_of_Studies: Number of Studies at this site ANNO: ANNO tag displayed the most important variant type that happened at GENE. Please see https://genome.sph.umich.edu/wiki/TabAnno for more information. ANNOFULL: ANNOFULL tag is the full set of annotation. Please see https://genome.sph.umich.edu/wiki/TabAnno for more information.