Title: Public-Use Data from the Obstetrics and Periodontal Therapy (OPT) Study, a randomized trial of periodontal therapy to prevent pre-term birth Creator(s): James S. Hodges -- author of record in Digital Conservancy Agreement Bryan S. Michalowicz -- Principal Investigator of the OPT Study Citation to paper(s): Main paper: Michalowicz BS, Hodges JS, DiAngelis AJ, Lupo VR, Novak MJ, Ferguson JE, Buchanan W, Bofill J, Papapanou PN, Mitchell DA, Matseoane S, Tschida PA; OPT Study. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med. 2006 Nov 2;355(18):1885-94. Secondary papers: Michalowicz BS, DiAngelis AJ, Novak MJ, Buchanan W, Papapanou PN, Mitchell DA, Curran AE, Lupo VR, Ferguson JE, Bofill J, Matseoane S, Deinard AS Jr, Rogers TB. Examining the safety of dental treatment in pregnant women. J Am Dent Assoc. 2008 Jun;139(6):685-95. Novak MJ, Novak KF, Hodges JS, Kirakodu S, Govindaswami M, Diangelis A, Buchanan W, Papapanou PN, Michalowicz BS. Periodontal bacterial profiles in pregnant women: response to treatment and associations with birth outcomes in the obstetrics and periodontal therapy (OPT) study. J Periodontol. 2008 Oct;79(10):1870-9. Kirakodu SS, Govindaswami M, Novak MJ, Ebersole JL, Novak KF. Optimizing qPCR for the Quantification of Periodontal Pathogens in a Complex Plaque Biofilm. Open Dent J. 2008;2:49-55. Epub 2008 Mar 11. Michalowicz BS, Hodges JS, Novak MJ, Buchanan W, DiAngelis AJ, Papapanou PN, Mitchell DA, Ferguson JE, Lupo VR, Bofill J, Matseoane S. Change in Periodontitis during Pregnancy and Risk of Preterm Birth and Low Birthweight. J Clin Periodontol 2009; 36(4):308-314. (PMCID 85882) Ebersole JL, Novak MJ, Michalowicz BS, Hodges JS, Steffen MJ, Ferguson JE, Diangelis A, Buchanan W, Mitchell DA, Papapanou PN. Systemic Immune Responses in Pregnancy and Periodontitis: Relationship to Pregnancy Outcomes in the Obstetrics and Periodontal Therapy (OPT) Study. J Periodontol. 2009;80(6):953-60. Michalowicz BS Novak MJ, Hodges JS, DiAngelis A, Buchanan W, Papapanou PN, Mitchell DA, Ferguson II JE, Lupo V, Bofill J, Matseoane S, Steffen M, Ebersole JL. Serum Inflammatory Mediators in Pregnancy: Changes Following Periodontal Treatment and Association with Pregnancy Outcomes. J Periodontol 80(11):1731-41, 2009. (PMCID: 127426) Ebersole JL, Stevens J, Steffen MJ, Dawson III D, Novak MJ. Systemic endotoxin levels in chronic indolent periodontal infections. J Periodont Res 2010; 45: 1–7.