This readme.txt file was generated on 20200615 by Sam Nemanich ------------------- GENERAL INFORMATION ------------------- 1. Title: Individualized anodal transcranial direct current stimulation increases corticospinal excitability in children with hemiparesis due to early stroke: transcranial magnetic stimulation assessment data 2. Author Information Principal Investigator Contact Information Name: Bernadette Gillick, PhD, MSPT, PT Institution: University of Minnesota Address: 420 Delaware St SE, MMC 388 Minneapolis, MN 55455 Email: gillick@umn.edu ORCID: Associate or Co-investigator Contact Information Name: Samuel Nemanich, PhD, MSCI Institution: Marquette University Address: 1700 Bldg, Room 140, PO Box 1881, Milwaukee, WI 53201 Email: sam.nemanich@marquette.edu ORCID: 0000-0001-6093-7266 Full author list: Nemanich, Samuel T Lench, Daniel H Sutter, Ellen N Kowalski, Jesse L Francis, Sunday Meekins, Greg Krach, Linda Feyma, Tim Gillick, Bernadette T 3. Date of data collection (single date, range, approximate date) 20180701-20200223 4. Geographic location of data collection (where was data collected?): Minneapolis, MN 5. Information about funding sources that supported the collection of the data: National Center of Neuromodulation for Rehabilitation (NCNM4R) http://academicdepartments.musc.edu/ncnm4r/ University of Minnesota Medical School -------------------------- SHARING/ACCESS INFORMATION -------------------------- 1. Licenses/restrictions placed on the data: CC0 1.0 Universal 2. Links to publications that cite or use the data: TBD 3. Links to other publicly accessible locations of the data: N/A 4. Links/relationships to ancillary data sets: N/A 5. Was data derived from another source? No 6. Recommended citation for the data: Nemanich, Samuel T; Lench, Daniel H; Sutter, Ellen N; Kowalski, Jesse L; Francis, Sunday; Meekins, Greg; Krach, Linda; Feyma, Tim; Gillick, Bernadette T. (2020). Individualized anodal transcranial direct current stimulation increases corticospinal excitability in children with hemiparesis due to early stroke: transcranial magnetic stimulation assessment data. Retrieved from the Data Repository for the University of Minnesota, http://hdl.handle.net/11299/213923. --------------------- DATA & FILE OVERVIEW --------------------- 1. File List A. Filename: N## Short description: Matlab data structure file (.mat). ## is an integer 01-21, omitting N10 and N18 (19 total files) B. Filename: README.txt Short description: Additional information about the dataset 2. Relationship between files: None, but all .mat files have same structure 3. Additional related data collected that was not included in the current data package: 4. Are there multiple versions of the dataset? no -------------------------- METHODOLOGICAL INFORMATION -------------------------- 1. Description of methods used for collection/generation of data: Transcranial magnetic stimulation of the motor cortex, electromyography of hand and wrist musculature. Manuscript link TBD 2. Methods for processing the data: Individual median was calculated for each metric from a total of 20 trials. 3. Instrument- or software-specific information needed to interpret the data: Matlab v2017 or above 4. Standards and calibration information, if appropriate: 5. Environmental/experimental conditions: Measures collected at 6 time points: Baseline, Post0, Post15, Post30, Post45, Post 60 (0, 15, 30, 45, 60 minutes after the intervention) 6. Describe any quality-assurance procedures performed on the data: 7. People involved with sample collection, processing, analysis and/or submission: ----------------------------------------- DATA-SPECIFIC INFORMATION FOR: N##.BasicInfo ----------------------------------------- **This dataset contains 19 individuals (N01-N21, excl N10 and N18) with stroke and hemiparesis, age 7-22. Data are stored in Matlab data structures, which contain a table and two sub-structures: 1. BasicInfo (table): demographics, group assignment 2. LesionedHemisphere (sub-structure): MEP data for lesioned hemisphere single-pulse TMS 3. NonlesionedHemisphere (sub-structure): MEP data for non-lesioned hemisphere single-pulse TMS The data in the two sub-structures contain Matlab 6 tables, one for each time point: 1. Pre (i.e. Baseline) 2. Post0 (0 minutes after tDCS) 3. Post15 (15 minutes after tDCS) 4. Post30 (30 minutes after tDCS) 5. Post45 (45 minutes after tDCS) 6. Post60 (60 minutes after tDCS) These tables contain a 20x24 array. Each row is an individual trial, each column is defined as follows: Left hand muscle (Channel 1) Column 1: Valid trial 1=yes, 0=no Column 2: MEP amplitude (uV) Column 3: MEP latency (ms) Column 4: MEP AUC Column 5: MEP number of peaks Column 6: MEP duration (ms) Columns 7-12: same as 1-6 for Right Hand muscle (Channel 2) Columns 12-18: same as 1-6 for Left Wrist muscle (Channel 3) Columns 19-24: same as 1-6 for Right Wrist muscle (Channel 4) **For all data in Matlab tables, use the command table2array to convert the table to a numeric matrix. 1. Number of variables: 3 2. Number of cases/rows: varies 3. Missing data codes: NaN Data were unable to be collected or were missing 0 Used as an identifier for each set as to if include a trial in analysis (0=exclude/invalid) 4. Variable List (for each N##.mat) A. Name: BasicInfo (1 row, 6 column) Description: Subject characterstics Column 1 = Age (in years) Column 2 = Sex Male Female Column 3 = MACS (Manual Abilities Classification Scale) I = Mild II = Mild-Moderate III = Moderate IV = Moderate-Severe V = Severe Column 4 = AffSide (Side of Hemiparesis) Left Right Column 5 = MEPyes (MEP present in lesioned hemisphere? Y = MEP present N = MEP absent Column 6 = Group Sham = Sham tDCS Real = Real tDCS B. Name: LesionedHemisphere (20 row, 24 columns) Description: Neurophysiologic variables obtained from stimulation of lesioned hemisphere Row 1-20 = Trial 1-20 Column 6*(n-1)+1: Valid trial 1=yes, 0=no Column 6*(n-1)+2: MEP amplitude (microVolts) Column 6*(n-1)+3: MEP latency (milliseconds) Column 6*(n-1)+4: MEP AUC (microVolts * milliseconds) Column 6*(n-1)+5: MEP number of peaks (integer) Column 6*(n-1)+6: MEP duration (milliseconds) n= Data= 1 Left Hand 2 Right Hand 3 Left Wrist 4 Right Wrist C. Name: NonLesionedHemisphere (20 rows, 24 columns) Description: Neurophysiologic variables obtained from stimulation of non-lesioned hemisphere Same as in B.