There is not enough evidence to make definitive recommendations for PSA as a screening tool for men younger than 75 years. In depth discussion regarding patient’s definition of quality of life is necessary to address the potential risks and benefits of screening and potential disease. This includes both psychological effects of false positive test as well as physiological side effects of surgery. It is likely that many more years of data will be necessary to correctly evaluate current effectiveness of monitoring protocols. It is necessary to note that PSA screening alone can have serious psychological effects on patients no matter the result.
Prostate-specific antigen is not an effective screening test for prostate cancer.
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