Many immigrants in the Twin Cities area come from areas where TB is endemic, and BCG vaccination in infancy is a standard part of TB control efforts. PPD testing is a widely used screening tool in the US, but concern for cross-reactivity in BCG-vaccinated patients may confuse results. This study shows that PPD testing may be used to screen for tuberculosis in adults that were vaccinated with BCG vaccination during infancy. A cutoff induration of 15mm should be used to define a positive PPD test regardless of BCG vaccination status.
PPD testing is a valid screening tool for tuberculosis infection in individuals vaccinated with BCG.
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