Objective: To evaluate the accuracy of a questionnaire designed for the identification of intraoral pain with neuropathic characteristics in a clinical orofacial pain sample population. Methods: 136 participants with 4 orofacial pain diagnoses (temporomandibular disorders [TMD, n=41], acute dental pain [ADP, n=41], trigeminal neuralgia (TN, n=19), persistent dentoalveolar pain disorder [PDAP, n=14]) and a group of pain-free controls (n=21) completed the modified S-LANSS, an adaptation of the original questionnaire devised to detected patients suffering from intraoral pain with neuropathic characteristics. Psychometric properties (sensitivity, specificity, positive predictive value [PPV], negative predictive value [NPV]) were calculated in two analyses with two different thresholds: 1) Detection of pain with neuropathic characteristics: PDAP + TN were considered positive, and TMD + ADP + controls were considered negative per gold standard (expert opinion). 2) Detection of PDAP: PDAP was considered positive and TMD + ADP were considered negative per gold standard. For both analyses, target values for adequate accuracy were defined as ≥80% for sensitivity and specificity. Results: For detection of orofacial pain with neuropathic characteristics (PDAP + TN), the modified S-LANSS presented with the most optimistic threshold sensitivity of 52% (95% CI: 34-69%), specificity of 70% (95% CI: 60-79%), PPV of 35% (95% CI: 22-51%), and NPV of 82% (95% CI: 72-89%). For detection of PDAP only, with the most optimistic threshold sensitivity was 64% (95% CI: 35-87%), specificity 63% (95% CI: 52-74%), PPV 23% (95% CI: 11-39%) and NPV 91% (95% CI: 81-97%). Conclusion: Based on a priori defined criteria, the modified S-LANSS did not show adequate accuracy to detect intraoral pain with neuropathic characteristics in a clinical orofacial pain population.
University of Minnesota M.S. thesis. March 2016. Major: Dentistry. Advisor: Donald Nixdorf. 1 computer file (PDF); vi, 28 pages.
Herrero Babiloni, Alberto.
Assesing Criterion Validity Of The Modified S-Lanss For The Detection Of Neuropathic Orofacial Pain Conditions.
Retrieved from the University of Minnesota Digital Conservancy,
Content distributed via the University of Minnesota's Digital Conservancy may be subject to additional license and use restrictions applied by the depositor.