Vinpocetine (VP) is a derivative obtained from (+) vincamine, and is commonly extracted from periwinkle. It has been shown to alleviate risks associated with stroke by enhancing cerebral blood flow. VP is also useful for the treatment of epilepsy and for the prevention of dementia. Current research is examining whether VP’s therapeutic effect is due to its active metabolite, AVA.
This research was supported by the Undergraduate Research Opportunities Program (UROP).
Gao, Robert; Paz, Matt.
Development of an Analytical Assay for the Determination of Vinpocetine’s Primary Metabolite, Apovincaminic Acid, in Human Plasma.
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